研究業績2012年度 英文原著


1.Ando Y, Coelho T, Berk JL, Cruz MW, Ericzon BG, Ikeda S, Lewis WD, Obici L, Planté-Bordeneuve V, Rapezzi C, Said G, Salvi F:

Guideline of transthyretin-related hereditary amyloidosis for clinicians.

Orphanet J Rare Dis 8:31, 2013


2.Abd Allah F, Majidi S, Watanabe M, Cahudhry SA, Qureshi AI:

Feasibility and validation of spinal cord vasculature imaging using high resolution ultrasound.

J Vasc Surg 56: 637-43, 2012


3.Abdihalim M, Watanabe M, Chaudhry SA, Jagadeesan B, Suri MF, Qureshi AI:

Are coil compaction and aneurysmal growth two distinct etiologies to recurrence following endovascular treatment of intracranial aneurysm.

J Neuroimaging 2013, in press


4.Asonuma K, Ohya Y, Isono K, Takeichi T, Yamamoto H, Lee KJ, Okumura K, AndoY, Inomata Y:

Current state of domino transplantation in Japan in terms of surgical procedures and de novo amyloid neuropathy.

Amyloid 19 Suppl 1: 75-77, 2012


5.Berk JL, Suhr OB, Sekijima Y, Yamashita T, Heneghan M, Zeldenrust SR, Ando Y, Ikeda S, Gorevic P, Merlini G, Kelly JW, Skinner M, Bisbee AB, Dyck PJ, Obici L, Familial Amyloidosis Consortium:

The Diflunisal Trial: study accrual and drug tolerance.

Amyloid 19 Suppl 1: 37-38, 2012


6.Chaudhry SA, Tariq N, Majidi S, Afzal MR, Hassan AE, Watanabe M, Rodriguez GJ, Suri MF, Hussain S, Qureshi AI:

Rates and factors associated with admission in patients presenting to the ED with TIA in the United States-2006 to 2008.

Am J Emerg Med 31: 516-519, 2013


7.Hayashi Y, Higashi T, Motoyama K, Mori Y, Jono H, Ando Y, Arima H:

Design and evaluation of polyamidoamine dendrimer conjugate with PEG, a-cyclodextrin and lactose as a novel hepatocyte-selective gene carrier in vitro and in vivo.

J. Drug Target, in press


8.Hayashi Y, Mori Y, Yamashita S, Motoyama K, Higashi T, Jono H, Ando Y, Arima H:

Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.

Mol Pharm 9: 1645-1653, 2012


9.Hayashi Y, Mori Y, Higashi T, Motoyama K, Jono H, Sah DW, Ando Y, Arima H:

Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.

Amyloid 19 Suppl 1: 47-49, 2012


10.Hirano T, Sasaki M, Tomura N, Ito Y, Kobayashi S for the J-ACT Group:

Low ASPECTS within 3 hours of onset predicts subsequent symptomatic intracranial hemorrhage in patients treated with 0.6 mg/kg alteplase.

J Stroke Cerebrovasc Dis 21: 898-902, 2012


11.Ikeda T, Kimura E, Hirano T, Uchino M:

The association between dermatomyositis and papillary thyroid cancer: A case report.

Rheumatol Int 32: 959-961, 2012


12.Ishizaki M, Ueyama H, Nishida Y, Imamura S, Hirano T, Uchino M:

Crossed aphasia following an infarction in the right corpus callosum.

Clin Neurol Neurosurg 114: 161-165, 2012


13.Inatomi Y, Nakajima M, Yonehara T, Hirano T: 

Contralateral recurrence of carotidynia during steroid therapy.

J Stroke Cerebrovasc Dis, in press


14.Jono H, Anno T, Motoyama K, Misumi Y, Tasaki M, Oshima T, Mori Y, Mizuguchi M, Ueda M, Shinriki S, Shono M, Obayashi K, Arima H, AndoY:

Potential use of glucuronylglucosyl-β-cyclodextrin as a novel therapeutic tool for familial amyloidotic polyneuropathy.

Amyloid 19 Suppl 1: 50-52, 2012


15.Kai Y, Ohmori Y, Watanabe M, Kaku Y, Morioka M, Hirano T, Kawano T, Hamada J, Kuratsu J:

A 6-Fr guiding catheter (Slim Guide®) for use with multiple microdevices.

Surg Neurol Int 3: 59, 2012


16.Kawano H, Hirano T, Inatomi Y, Terasaki T, Yonehara T, Uchino M:

Hyperacute-Phase Computed Tomography-Diffusion-Weighted Imaging Discrepancy and Response to Thrombolysis.

J Stroke Cerebrovasc Dis: 2012, in press


17.Kawano H, Hirano T, Nakajima M, Inatomi Y, Yonehara T, Uchino M: 

Modified ASPECTS for DWI including deep white matter lesions predicts subsequent intracranial hemorrhage.

J Neurol 259, 2045-2052, 2012


18.Kawano H, Inatomi Y, Hirano T, Yonehara T:  

Vertebral artery stump syndrome in acute ischemic stroke.

J Neurol Sci 324:74-79, 2013


19.Kawano H, Hirano T, Inatomi Y, Yonehara T: 

Cerebral infarction in both carotid and vertebrobasilar territories associated with a persistent primitive hypoglossal artery with severe dilated cardiomyopathy.

J Stroke Cerebrovasc Dis, 2013, in press


20.Kawano H, Hirano T, Nakajima M, Inatomi Y, Yonehara T: 

Diffusion-weighted MR imaging may underestimate acute ischemic lesions – Cautions on neglecting a CT – DWI discrepancy.

Stroke 44:1056-1061, 2013


21.Kimura N, Kumamoto T, Masuda T, Hanaoka T, Okazaki T, Arakawa R:

Evaluation of the regional cerebral blood flow changes during long-term donepezil therapy in patients with Alzheimer’s disease using 3DSRT.

J Neuroimaging 22: 299-304, 2012


22.Matsuo Y, Yamashita S, Honda S, Nakajima M, Ueda A, Hirahara T, Yamashita T, Maeda Y, Hirano T, Ando Y: 

Bilateral basal ganglia lesions as initial manifestation of CNS invasion in adult T-cell leukemia.

J Neurol Sci, 327: 63-64, 2013


23.Majidi S, Hassan A, Watanabe M, Sein J, Van de Moortele PF, Clark HB, Suri F, Qureshi AI:

Intracranial Derived Atherosclerosis Assessment: An In-vitro Comparison between Virtual Histology by Intravascular Ultrasonography, 7-Tesla MRI and Histopathological Findings.

AJNR 2013, in press


24.Majidi S, Grigoryan M, Tekle WG, Watanabe M, Qureshi AI:

Feasibility of using intravascular ultrasonography for assessment of giant cavernous aneurysm after endovascular treatment: atechnical report.

J Vasc Interv Neurol 5:6-9, 2012


25.Majidi S, Khatri R, Watanabe M, Siddiq F, Chaudhry S, Qureshi A:

Aneurysm Embolization Using Detachable Coils Under Intravascular Ultrasonography (IVUS) : Guidance: An In-Vitro Feasibility Study.

Neurosurgery 70: 1557-1564, 2012


26.Misumi I, Fujimoto A, Ishizaki M, Masuda T, Nishida Y, Tateishi M, Tawara A, Ueyama H, Imamura S, Matsumoto M, Sugiyama S, Ogawa H:

Left ventricular undulation in a patient with atrial flutter.

J Echocardiogr 10: 74-76, 2012


27.Misumi Y, Ueda M, Obayashi K, Jono H, Su Y, Yamashita T, Oshima T, Ando Y, Uchino M:

Relationship between amyloid deposition and intracellular structural changes in familial amyloidotic polyneuropathy.

Hum Pathol 43: 96-104, 2012


28.Misumi Y, Ueda M,Obayashi K, Jono H, Yamashita T, Ando Y: 

Interaction between amyloid fibril formation and extracellular matrix in the proceedings of VIIIth International Symposium on Familial Amyloidotic Polyneuropathy.

Amyloid 19 Suppl 1: 8-10, 2012


29.Motomiya Y, Uji Y, Ando Y:

Capillary electrophoretic profile of β2-microglobulin intermediate associated with hemodialysis.

Ther Apher Dial 16: 350-354, 2012


30.Nakajima M, Inatomi Y, Yonehara T, Hashimoto Y, Hirano T, Uchino M:

Oral intake 6 months after acute ischemic stroke.

Intern Med 51: 45-50, 2012


31.Nakajima M, Inatomi Y, Yonehara T, Hirano T, Uchino M:

Rotational vertigo associated with putaminal infarction.

J Stroke Cerebrovasc Dis 21: 912. e9-10, 2012


32.Nakajima M, Inatomi Y, Yonehara T, Hashimoto Y, Hirano T: 

Acquisition of oral intake in severely dysphagic patients with acute stroke: A single-center, observational study involving a database of 4972 consecutive stroke patients.

J Neurol Sci 323: 56-60, 2012


33.Nakajima M, Inatomi Y, Yonehara T, Okigawa T, Hirano T: 

Secondary signal change and an apparent diffusion coefficient decrease of the substantia nigra following striatal infarction.

Stroke 44: 213-216, 2013


34.Naganuma M, Isoda K, Nishi S, Ito K, Hirano T: 

Repeated episodes of ischemic stroke over a short period in a patient with essential thrombocythemia on anticoagulant therapy.

J Stroke Cerebrovasc Dis, in press


35.Migita K, Ando Y, Takaoka H, Suzushima H, Shiraishi N:

Amyloid A amyloidosis in a Japanese patient with familial Mediterranean fever associated with homozygosity for the pyrin variant M694I/M694I.

Mod Rheumatol, in press


36.Obayashi K, Oshima T, Tasaki M, Suhr OB, Anan I, Misumi Y, Ueda M, Yamashita T, Jono H, Ando Y:

Detection of autoantibodies against ATTR in patients with FAP ATTR V30M.

Amyloid 2013, in press.


37.Obayashi K, Ando Y: 

Focus on autonomic dysfunction in familial amyloidotic polyneuropathy (FAP).

Amyloid 19 Suppl 1: 28-29, 2012


38.Obayashi K, Ueda M, Oshima T, Kawahara S, Misumi Y, Yamashita T, Jono H, Yazaki M, Kametani F, Ikeda S, Ohya Y, Asonuma K, Inomata Y, Ando Y: 

Pathological changes long after liver transplantation in a familial amyloidotic polyneuropathy patient.

BMJ Case Rep, in press


39.Obayashi K, Tasaki M, Jono H, Ueda M, Shinriki S, Misumi Y, Yamashita T, Oshima T, Nakamura T, Ikemizu S, Anan I, Suhr O, Ando Y: 

Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine.

Clin Chim Acta 419:127-131, 2013


40.Ohya Y, Isono K, Obayashi K, Hayashida S, Lee KJ, Yamamoto H, Takeichi T, Asonuma K, Ando Y, Inomata Y:

Peritransplant Gastrointestinal Symptoms in Familial Amyloidotic Polyneuropathy.

Exp Clin Transplant, in press


41.Ohsawa Y, Okada T, Nishimatsu S, Ishizaki M, Suga T, Fujino M, Murakami T, Uchino M, Tsuchida K, Noji S, Hinohara A, Shimizu T, Shimizu K, Sunada Y:

An inhibitor of transforming growth factor beta type I receptor ameliorates muscle atrophy in a mouse model of caveolin 3-deficient muscular dystrophy.

Lab Invest, 92:1100-1114, 2012


42.Okabe H, Beppu T, Ueda M, Hayashi H, Ishiko T, Masuda T, Otao R, Horlad H, Mima K, Miyake K, Iwatsuki M, Baba Y, Takamori H, Jono H, Shinriki S, Ando Y, Baba H:

Identification of CXCL5/ ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts.

Int J Cancer 131: 2234-2241, 2012


43.Ota T, Jono H, Ota K, Shinriki S, Ueda M, Sueyoshi T, Nakatani K, Hiraishi Y, Wada T, Fujita S, Obayashi K, Shinohara M, Ando Y:

Downregulation of midkine induced cisplatin resistance in human squamous cell cartinoma.

Onco report 27: 1674-1680, 2012


44.Piazza F, Greenberg SM, Savoiardo M, Gardinetti M, Chiapparini L, Raicher I, Nitrini R, Sakaguchi H, Brioschi M, Billo G, Colombo A, Lanzani F, Piscosquito G, Carriero MR, Giaccone G, Tagliavini F, Ferrarese C, DiFrancesco JC:

Anti-Aβ autoantibodies in Cerebral Amyloid Angiopathy-related inflammation: implications for amyloid-modifying therapies.

Annals of Neurology, 2013, in press.


45.Qureshi AI, Chaudhry SA, Connelly B, Abott E, Janjua T, Kim SH, Miley JT, Rodriguez GJ, Uzun G, Watanabe M: 

Impact of advanced health care directives on treatment decisions by physicians in patients with acute stroke.

Crit Care Med 2012, in press


46.Sakaguchi H, Yamashita S, Hirano T, Nakajima M, Kimura E, Maeda Y, Uchino M: 

Myasthenic crisis patients who require ICU management.

Muscle Nerve 46:440-442, 2012


47.Sakaguchi H, Yamashita S, Suga T, Kimura E, Maeda Y, Hirano T, Uchino:

Multiple system atrophy in a patient with primary ciliary dyskinesia.

Neurology Asia 18: 103-105, 2013


48.Shirahama K, Inatomi Y, Yonehara T, Hirano T, Uchino M:

Recurrence of embolic stroke during intravenous thrombolysis.

J Stroke Cerebrovasc Dis 21: 84-86, 2012


49.Somekawa-Kondo T, Yamaguchi K, Ishitsuka Y, Itoa S, Tanaka K, Irikura M, Moriuchi H, Takahama K, Ando Y, Yamasaki T, Irie T:

Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea pigs.

J Pharm Phatmacol 65:102-114, 2013.


50.Su Y, Misumi Y, Ueda M, Shono M, Tasaki M, Jono H, Obayashi K, Senokuchi T, Yamagata K, Ando Y: 

The occurrence of islet amyloid polypeptide amyloidosis in Japanese subjects.

Pancreas 41: 971-973, 2012


51.Su Y, Jono H, Torikai M, Hosoi A, Soejima K, Guo J, Tasaki M, Misumi Y, Ueda M, Shinriki S, Shono M, Obayashi K, Nakashima T, Sugawara K, Ando Y: 

Antibody therapy for familial amyloidotic polyneuropathy.

Amyloid 19 Suppl 1: 45-46, 2012


52.Su Y, Jono H, Misumi Y, Senokuchi T, Guo J, Ueda M, Shinriki S, Tasaki M, Shono M, Obayashi K, Yamagata K, Araki E, Ando Y: 

Novel function of transthyretin in pancreatic alpha cells.

FEBS Lett 586: 4215-4222, 2012


53.Sueyoshi T, Jono H, Shinriki S, Ota K, Ota T, Tasaki M, Atsuyama E, Yakushiji T, Ueda M, Obayashi K, Mizuta H, Ando Y: 

Therapeutic approaches targeting midkine suppress tumor growth and lung metastasis in osteosarcoma.

Cancer Lett 316: 23-30, 2012


54.Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe KI, Kimura E, Sakurai H:

Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro.

PLoS One 8: e61540, 2013


55.Tanaka T, Nakayama H, Yoshitake Y, Irie A, Nagata M, Kawahara K, Takamune Y, Yoshida R, Nakagawa Y, Ogi H, Shinriki S, Ota K, Hiraki A, Ikebe T, Nishimura Y, Shinohara M:

Selective inhibition of nuclear factor-κB by nuclear factor-κB essential modulator-binding domain peptide suppresses the metastasis of highly metastatic oral squamous cell carcinoma.

Cancer Sci 103: 455-463, 2012


56.Tokunaga M, Watanabe S, Nakanishi R, Yamanaga H, Kawasaki M, Hirata Y, Yamaga M, Terasaki T, Hashimoto Y, Sonoda S:

Mean length of stay and rate of discharge to home adjusted for severity in rehabilitation hospitals participating in Kumamoto stroke liaison critical pathway.

Jpn J Compr Rehabil Sci 3: 26-31, 2012


57.Tokunaga M, Yonemura M, Inoue R, Sannomiya K, Nakashima Y, Watanabe S, Nakanishi R, Yamanaga H, Yonemitsu H, Sonoda S:

Effects of age on functional independence measure score gain in stroke patients in kaifukuki rehabilitation ward.

Jpn J Compr Rehabil Sci 3: 32-36, 2012


58.Tokunaga M, Watanabe S, Nakanishi R, Yamanaga H, Kawasaki M, Hirata Y, Yamaga M, Terasaki T, Hashimoto Y, Sonoda S:

Relationship between hospital ranking based on Functional Independence Measure (FIM) efficiency and factors related to rehabilitation system for stroke patients.

Jpn J Compr Rehabil Sci 3: 51-58, 2012


59.Tokunaga M, Watanabe S, Nakanishi R, Yamanaga H, Sannomiya K, Hirata Y, Yamaga M, Terasaki T, Hashimoto Y, Sonoda S:

Comparison between convalescent rehabilitation hospitals participating in the stroke liaison critical pathway with respect to the gain of Nichijo-seikatsu-kino-hyokahyo score.

Jpn J Compr Rehabil Sci 3: 11-17, 2012


60.Uchino M, Yamashita S, Uchino K, Mori A, Hara A, Suga T, Hirahara T, Koide T, Kimura E, Yamashita T, Ueda A, Kurisaki R, Suzuki J, Honda S, Maeda Y, Hirano T, Ando Y: 

Muscle biopsy findings predictive of Malignancy in rare infiltrative dermatomyositis.

Clin Neurol Neurosurg 115: 603-606, 2013


61.Uchino M, Yamashita S, Uchino K, Hara A, Koide T, Suga T, Hirahara T, Kimura E, Yamashita T, Ueda A, Kurisaki R, Suzuki J, Honda S, Maeda Y, Hirano T:

Long-term Outcome of Polymyositis Treated with High Single-dose Alternate-day Prednisolone Therapy.

Eur Neurol 68: 117-121, 2012


62.Uji Y, Motomiya Y, Ando Y: 

Effect of Heparin on Conformation of the β(2) -Microglobulin Molecule.

Ther Apher Dial, 16: 159-162, 2012


63.Ueda M, Ageyama N, Nakamura S, Nakamura M, Chambers J, Misumi Y, Mizuguchi M, Shinriki S, Kawahara S, Tasaki M, Jono H, Obayashi K, Sasaki E, Une Y, Ando Y: 

Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: A valid pathological model of the human disease.

Lab Invest 92: 474-484, 2012


64.Watanabe M, Siddiqui F, Qureshi AI:

Incidence and Management of Ischemic Stroke and Intracerebral Hemorrhage in Patients on Dabigatran Etexilate Treatment.

Neurocritical Care 16: 203-209, 2012


65.Watanabe M, Siddiqui F, Qureshi AI:

Periprocedural Management of Patients on Dabigatran Etexilate Treatment.

AJNR 38:E166, 2012


66.Watanabe M, Majidi S, Chaudhry SA, Qureshi AI:

The chronological change of echogenicity and histological correlates of experimental blood clots. A serial ultrasound study.

J Ultrasound Med 31:1987-1992, 2012


67.Watanabe M, Qureshi AI:

Are CT Angiography Source Images Accurate for Evaluating Infarct Volume?

J Neuroimaging 2012, in press


68.Watanabe M, Siddiqui F, Qureshi AI:

Periprocedural Management of Patients on Dabigatran Etexilate Treatment.

AJNR 32:E214, 2012


60.Watanabe M, Kai Y, Hirano T, Ohmori Y, Kazekawa K, Kuratsu J:

Manual external carotid artery manipulation for failed device advance through the stent in carotid artery stent placement. A technical note.

J Vasc Interv Neurol 2013, in press


70.Watanabe M, Semaan E, Majidi S, Chaudhry SA, Adil MM, Alqadri S, Qureshi AI:

Treatment of cerebral dural sinus stenosis using stent placement: a systematic review.

J Vasc Interv Neurol 2013, in press


71.Watanabe M, Majidi S, Chaudhry SA, Qureshi AI:

The severity of intracranial stenosis in anterior circulation correlates with asymmetrical hemispheric cerebral volume on magnetic resonance imaging.

J Vasc Interv Neurol 2013, in press


72.Watari M, Nakajima M, Nishitomi-Izumida M, Inatomi Y, Yonehara T, Hirano T:

Dynamic migration of a mobile plaque from the brachiocephalic artery detected by ultrasonography.

Echocardiography 30:E28-29, 2013


73.Wixner J, Obayashi K, Ando Y, Karling P, Anan I:

Loss of gastric interstitial cells of Cajal in patients with hereditary transthyretin amyloidosis.

Amyloid, 2013, in press.


74.Yamashita S, Kimura E, Tawara N, Sakaguchi H, Nakama T, Maeda Y, Hirano T, Uchino M, Ando Y: 

Optineurin is potentially associated with TDP-43 and involved in the pathogenesis of inclusion body myositis. Neuropathol.

Appl. Neurobiol, 39, 406-416, 2013


75.Yamashita S, Mori A, Sakaguchi H, Suga T, Ishihara D, Ueda A, Yamashita T, Maeda Y, Uchino M, Hirano T: 

Sporadic juvenile amyotrophic lateral sclerosis caused by mutant FUS/TLS: Possible association of mental retardation with this mutation.

J Neurol 259:1039-1044, 2012


76.Yamashita S, Uchida Y, Kojima S, Sakaguchi H, Kimura E, Maeda Y, Uchino M: 

Heatstroke in patients with Parkinson’s disease.

Neurol Sci33: 685-687, 2012


77.Yamashita S, Sakaguchi H, Mori A, Kimura E, Maeda Y, Hirano T, Uchino M:

Significant CMAP decrement by repetitive nerve stimulation is more frequent in median than ulnar nerves of patients with amyotrophic lateral sclerosis.

Muscle Nerve 45: 426-428, 2012


78.Yamashita T, Ando Y, Okamoto S, Misumi Y, Hirahara T, Ueda M, Obayashi K, Nakamura M, Jono H, Shono M, Asonuma K, Inomata Y, Uchino M:

Long-term survival after liver transplantation in patients with familial amyloid polyneuropathy.

Neurology 78: 637-643, 2012

Copyright© Department of Neurology, Graduate School of Medical Sciences, Kumamoto University.